Date: 2008-11-25 10:45 am (UTC)
and I was trying to explain how it was thought to be a developmental defect rather than a mutation [...] it could just as easily be the chemical environment in the uterus at fault

Isn't that the definition of a developmental defect? In the absence of structural chromosomal abnormalities or monosomy/polysomy/polyploidy, you're only really left with environmental factors in utero as an explanation.
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